RAMCHANDER RAO NADIPELLY
Brookings,SD
Summary
Industry-trained virologist with 5+ years of experience in viral vaccine R&D, spanning COVID-19, influenza, polio, and PRRSV programs. Expert in cell-culture vaccine platforms, neutralization assays, animal models, and GLP-aligned preclinical development. Proven contributor to commercial vaccine pipelines and translational research.
Overview
6
6
years of professional experience
Work History
PhD Candidate – Vaccine & Translational Virology
South Dakota State University
Brookings
01.2022 - Current
- Performed qPCR, ELISA, and FMIA for PRRSV surveillance and outbreak analysis.
- Conducted whole-genome sequencing and phylogenetic analyses to inform vaccine strain selection. Led preclinical PRRSV vaccine studies, including dose optimization, clinical evaluation, necropsy procedures, and comprehensive tissue analysis.
- Designed recombinant vaccine efficacy studies measuring antibody, cytokine, and viral-load endpoints.
- Applied Illumina and Nanopore sequencing for viral genomics and host response analysis.
- Built 3D swine respiratory organoids for translational vaccine testing.
- Supported safety and immunogenicity evaluations of UVC-inactivated polio vaccine (ultraIPV) through collaborative partnerships with industry.
- Conducted rodent dosing, necropsy, and histological sample preparation, contributing to peer-reviewed vaccine validation studies.
- Demonstrated strong organizational and time management skills while managing multiple projects.
Executive – Virology Research & Vaccine Development
Bharat Biotech International Ltd
India
01.2020 - 01.2022
- Contributed to commercial COVID-19 (BBV154 intranasal), influenza, and viral-vectored vaccine programs.
- Performed PRNT, VNT, TCID50, HA, HI, SRID, NA assays for potency, stability, and lot release support.
- Led mammalian cell culture and virus expansion for vaccine manufacturing pipelines.
- Conducted HCP, HCD, and total protein assays and supported upstream/downstream process optimization.
- Mentored junior staff, fostering professional growth and enhancing team capabilities.
- Facilitated training sessions, promoting best practices in compliance and quality assurance standards.
- Assisted in recruiting, hiring and training of team members.
Education
Ph.D. - Veterinary Pathobiology
South Dakota State University
Brookings, SD01-2026
BVSc & AH -
PVNR Telangana Veterinary University
India07.2019
Skills
- Viral Vaccines (Inactivated, Recombinant, Viral-vectored) PRNT, VNT, TCID50 qPCR, ELISA, Western Blot, IFA
- Mammalian Cell Culture & Virus Propagation Animal Models (Rodent, Swine) Immunogenicity & Safety
- NGS (Illumina, Nanopore) Viral Genomics GLP, BSL-2 (BSL-3 training)
PUBLICATION
Nadipelly R, et al. Viruses (2025) – UVC-Inactivated Polio Vaccine (ultraIPV)
Timeline
PhD Candidate – Vaccine & Translational Virology
South Dakota State University
01.2022 - Current
Executive – Virology Research & Vaccine Development
Bharat Biotech International Ltd
01.2020 - 01.2022
Ph.D. - Veterinary Pathobiology
South Dakota State University
BVSc & AH -
PVNR Telangana Veterinary University